Introduction : Acute cholecystitis is a major complication of biliary lithiasis. Cholecystectomy is the gold standard treatment for gallbladder disease. According to the 2015 Statistics Office in Korea, 4.51% of the population is aged 80-89 years and 0.3%is aged 90-99 years. The safety and feasibility of cholecystectomy in octogenarians have been proven in many studies. In this study, we aimed to assess the outcomes of cholecystectomy in octogenarians and nonagenarians with acute cholecystitis

Methods : A total of 393 patientsaged 80-89 years (352 octogenarians) and 90-99 years (41 nonagenarians) diagnosed with acute cholecystitis underwent cholecystectomy between March 2012 and June 2020. All patients were classified according tothe Tokyo guidelines. The evaluated parameters included demographic data, surgical outcomes, American Society of Anesthesiologists score (ASA), and Tokyo guidelines. All data were analyzed with SPSS v1.0.0.1406.

Results : All 393 patients were analyzed and divided into two groups according to age: octogenarians(83.57?.64 years) and nonagenarians (92.98?.15 years). The survival rate was 97.7% for octogenarians and 97.6% for nonagenarians. Laparoscopic surgery was performed more in both groups (96.8% in octogenarians and 92.7% in nonagenarians) than open surgery (3.2% in octogenarians and 7.3% in nonagenarians). The incidences of postoperative complications in the octogenarian and nonagenarian groups were as follows: pneumonia, 5.7% and 7.3%; bleeding, 1.7% and 2.4%; gastrointestinal symptoms, 6.0% and 2.4%;

Conclusions : Cholecystectomy is a safe and efficient procedure for the treatment of acute cholecystitis in both octogenarians and nonagenarians