Detailed Abstract
[Plenary Session]
[PL 4] Minimal invasive distal pancreatectomy: Chronologic changes in the trends and clinical outcomes through an 15-Year single center experience with 2212 patients
Yejong PARK1, Dae Wook HWANG1, Jae Hoon LEE1, Ki Byung SONG1, Eunsung JUN1, 2, Woohyung LEE1, Jaewoo KWON1, Song Cheol KIM*1
1Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery,, University of Ulsan College of Medicine & Asan Medical Center, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, Korea, Korea
2Department of Convergence Medicine, Asan Institute for Life Sciences,, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea, Korea
Introduction : Based on the development and expansion of treatment strategies since the 2000s, we identify the chronologic changes of the clinical and postoperative outcomes of minimal invasive distal pancreatectomy (MIDP) for left-sided pancreatic tumor.
Methods : Between 2005 and 2019, 2212 patients underwent planned MIDP. The chronologic change in MIDP was analyzed according to procedure (Open distal pancreatectomy (OPD) vs. MIDP), age, spleen preserving, and maligancy. In addition, the difference in clinical and postoperative outcomes was identified by dividing the periods at 5-year intervals, and prognostic factors of open converison and severe postoperative complication were analyzed.
Results : MIDP has been increasing steadily over 15 years when comparing ODP (from 10.8% to 84.9%). Benign disease has a plateau pattern with a proportion of around 90% from 2010, but in Pancreatic ductal adenocarcinoma (PDAC), the proportion of MIDP from 5.6% to 68.4% has been steadily increasing. In the second half of 15 years, compared to the first five years, PDAC increased from 8.3% to 32.8%, and above all, the proportion of RAMPS increased significantly. The open conversion rate was 3.5%, and the risk factors for open conversion in multivariate logistic regression analysis was malignancy, extended pancreatectomy, and site of tumor lesion (body). Also, the poor prognostic factor of severe complication was malignancy, extended pancreatectomy, and ASA classification ≥3.
Conclusions : In Benign disease, MIDP is considered a standard procedure. However, MIDP at PDAC still has a technical and oncological challenge. We need high quality randomized controlled trials for acceptable of MIDP in PDAC.
Methods : Between 2005 and 2019, 2212 patients underwent planned MIDP. The chronologic change in MIDP was analyzed according to procedure (Open distal pancreatectomy (OPD) vs. MIDP), age, spleen preserving, and maligancy. In addition, the difference in clinical and postoperative outcomes was identified by dividing the periods at 5-year intervals, and prognostic factors of open converison and severe postoperative complication were analyzed.
Results : MIDP has been increasing steadily over 15 years when comparing ODP (from 10.8% to 84.9%). Benign disease has a plateau pattern with a proportion of around 90% from 2010, but in Pancreatic ductal adenocarcinoma (PDAC), the proportion of MIDP from 5.6% to 68.4% has been steadily increasing. In the second half of 15 years, compared to the first five years, PDAC increased from 8.3% to 32.8%, and above all, the proportion of RAMPS increased significantly. The open conversion rate was 3.5%, and the risk factors for open conversion in multivariate logistic regression analysis was malignancy, extended pancreatectomy, and site of tumor lesion (body). Also, the poor prognostic factor of severe complication was malignancy, extended pancreatectomy, and ASA classification ≥3.
Conclusions : In Benign disease, MIDP is considered a standard procedure. However, MIDP at PDAC still has a technical and oncological challenge. We need high quality randomized controlled trials for acceptable of MIDP in PDAC.
SESSION
Plenary Session
Room A 3/27/2021 11:45 AM - 12:00 PM